The prognosis of patients with metastatic or recurrent squamous cell carcinoma of the head and neck region
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چکیده
The prognosis of patients with metastatic or recurrent squamous cell carcinoma of the head and neck region (SCCHN) is generally poor, with a median survival of 5-9 months, depending on patient and disease-related factors. Selected patients with good performance status and locally recurrent disease may benefit from surgical salvage and/ or re-irradiation. For most patients with metastatic or advanced recurrent disease, treatment options include single agent chemotherapy, combination chemotherapy, targeted agents either alone or in combination with conventional chemotherapy, and best supportive care (Lane et al., 1968; Leone et al., 1968; Papac et al., 1978; Kirkwood et al., 1981; Pinto and Jacobs, 1991; Forastiere
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تاریخ انتشار 2013